乐盈彩票
您現在的位置:國藥控股湖南有限公司2018>> 公司新聞>> 醫藥信息>>正文內容

中國醫藥子公司非諾貝特膽堿獲CFDA批臨床

中國醫藥3月31日公告稱,下屬子公司天方藥業于近日收到CFDA核準簽發的非諾貝特膽堿原料《審批意見通知件》及緩釋膠囊《藥物臨床試驗批件》。

非諾貝特膽堿緩釋膠囊為雅培艾伯維(ABBVIE)于 2008 年 12 月在 FDA 上市的氯貝丁酸衍生物類血脂調節藥,上市產品商品名為 TRILIPIX,已在多國上市。經大量臨床實驗和藥物研究證實:非諾貝特的疏水性導致其生物利用度低,并且受食物的影響大,與非諾貝特相反,非諾貝特膽堿在小腸區有較高的溶解度,因此增加了非諾貝酸的生物利用度,并且生物利用度不受食物的影響,同時,使用劑量減少,毒副作用也隨之降低。通過化學修飾后的非諾貝特膽堿,是非諾貝特生物利用度終極解決方案,可以預見它將取代以往所有已上市的非諾貝特制劑,而且大大改善其療效,降低毒性。

目前本品未在國內上市,根據統計,艾伯維非諾貝特膽堿緩釋膠囊 2014 年銷售額約為 23,590 萬美元,2015 年銷售額約為 16,310 萬美元。

天方藥業于 2015 年 11 月 25 日向國家藥監局提交臨床試驗注冊申請。該類藥物的適應癥為調血脂藥,能降低嚴重高甘油三酯血癥患者的 TG,降低LDL-C,總膽固醇,TG 和載脂蛋白 B,使原發性高脂血癥患者或混合型血脂異常患者 HDL-C 升高。

截止公告日,天方有限在該類藥品研發項目上已累計投入研發費用約298萬元人民幣。

 

【字體: 】【打印文章

相關文章

    沒有相關內容
乐盈彩票
<nav id="w2ws4"><strong id="w2ws4"></strong></nav>
<menu id="w2ws4"><tt id="w2ws4"></tt></menu>
  • www.00829e.com | 11005n.com | www.boma0111.com | www.83033h.com | www.308139.com | lxs12333.com | www.00773u.com | www.530751.com | 6766ii.com | www.87708a.com | 3225s.com | www.373720.com | www.66376q.com | 97000.cc | www.239872.com | www.300388.com | 38345b.com | www.4996ah.com | www.424223.com | 98345l.com | www.7920k.com | gg1331.com | www.225430.com | www.570133.com | 2649kk.com | www.68993272.com | 21366l.com | www.pj88e.com | 1624aa.com | www.914511.com | www.602469.com | hg86855.com | www.50074g.com | 2737vip.com | www.4546100.com | x48n.com | www.7842.com | www.284488.com | www.737.am | www.2373k.com | 17998.cc | www.28891j.com | s86226.com | www.xpj8856.com | 2jsaaa.com | www.xpj16682.com | 4167v.com | www.19019e.com | 33p88.cc | www.163a44.com | 3225h.com | www.www6161msc.com | www.627793.com | www.63877z.com | www.738126.com | www.1111wns.com | www.737249.com | www.77077.com | www.607995.com | www.42424688.com | www.335324.com | www.dd7920.com | www.050955.com | www.sh8800.com | 01885b.com | www.374646.com | 33567u.com | www.77731v.com | biying930vip.com | www.k84551.com | www.89894w.com | www.53532.com | 9971001.com | www.zs5555.com | 777.com | www.3494.hk | www.88266v.com | www.3335js.com | 68455.com | www.945suncity.com | ahg5588.com | www.sbtyc.com | 1665a.com | www.47506n.com | 86611.com | www.588vip.cc | 131ttt.net | www.c71.cc | www.hg33733.com | www.26878e.com | www.pi111.com | 86811nn.com | www.115527x.com | 21549.com | www.hg09d.com | 5130ag.com | www.38775dd.com | douguo.com | www.34788l.com | www.2233524.com | www.178275.com | www.66h6.com | t365f.com | www.16181t.com | 6150a.com | www.6653d.com | www.ylg2206.com | www.217302.com | www.9199sun.com | 65056.com | www.js79901.com | hg77033.com | www.981060.com | www.941289.com | 8381q.com | www.686102c.com | u01234.com | www.hy5508.com | www.vm905.com | 2019f.cc | www.5502.app | www.22xpjdc.com | 188qq333.com | www.8899kcd.com | 6647u.com | www.33588e.com | www.9737hh.me | 8722uuuu.com | www.646452.com | www.2302325.com | 86811pp.com | www.8039r.com | www.44221.com | 6195jp.com | www.50024t.com | www.5395287.com | 4647055.com | www.35155q.com | www.ljw038.com | yinhe100.cc | www.55228c.com | www.hg22331.com | 20166.com | www.5856862.com | www.700h.com | www.668566.com | www.g27229.com | 364860.com | www.73166l.com | www.41230599.com | x33q.vip | www.927320.com | www.941289.com | yuhe.ooo | www.763826.com | www.848524.com | 500000595.com | 1005hh.com | www.75600v.com | www.hgbet66.com | 88335156.com | www.27czj.com | www.35252n.com | 66876e.com | 1429t.com | www.7239m.com | www.456228.com | 9149g.com | www.83033k.com | www.112351.com | 666cp.net | 86811j.com | www.16065r.com | www.282456.com | 563567.com | 1592n.com | www.0601v.com | www.zb623.com | 61788.com | www.yy63.com | www.xpj66696.com | www.hg1850.com | d2127002.com | www.558413.com | www.640268.com | www.2078h.com | 78115577.com | 61322277.com | www.71399r.com | www.33115rr.com | 5446xx.com | 3334136.com | www.550637.com | www.6133.com | www.hg8903.com | 61321133.com | feicai0516.com | www.927793.com | www.109115.com | www.2002900.com | 2jsbbb.com | pj12323.com | www.715613.com | www.3846.com | www.59909.com | 1098.com | 4508kk.com | qiangui002.com | www.55717f.com | www.666118a.com | 7736w.com | 3678dd.com | 73055v.com | www.333xm.cc | www.20hga.com | www.5319tt.com | 3685z.com | 3467v.am | 88905353.com | www.zmfqp.com | www.3157w.com | www.440887.com | 3009w.com | 7077a.com | 5853d.com | www.901512.com | www.048181.com | www.hg2886.com | www.330099x.com | 56988x.com | 51133ii.com | www.52072a.com | www.qilc7.com | www.99094q.com | www.jz95566.com | www.101vns.com | www.ab218.com | 2078c.com | wnsr8826.com | 6150b.com | www.645411.com | www.80075y.com | www.8099777.com | www.ra82.com | www.9547l.com | www.81866l.com | mm33.vip | 9339999k.com | 61789k.com | 3650580.com | www.810895.com | www.62118f.com | www.wns22.me | www.00618b.com | www.858t.com | www.09569z.com | www.668k8.com | 28288ll.com | ee40033.com | j84105.com | 34i35.com | feicai.cc | www.018916.com | www.837771.com | www.8667b.com | www.89894q.com | www.3398711.com | www.6052365.com | www.kj151.com | www.900651.com | www.38200i.com | 2883dl.com | 2554com.com | 7720743.com | 9694o.com | 56698.com | ah116.net | 3552a.com | 6868mm.cc | 3685e.com | www.43818e.com | www.299850.com | www.544091.com | www.757209.com | www.965160.com | www.rrle4.com | www.2350y.com | www.9149d.com | www.97714.com | www.1432Z.COM | www.365380dh.com | www.3155hd.com | www.126cpw.com | www.hb858.cc | www.1429.net | www.ya2019q.com | www.794478.com | www.ya2019k.com | www.635799.com | www.bet379.com | www.84499j.com | www.68689y.com | www.60108c.com | www.32123y.com | www.94580.cc | www.255ak.com | www.ya022.com | www.cp8003.cc | www.843633.com | www.163cp1.cc | www.330291.com | www.41518t.com | sxcxt.net | x45638.com | 53166l.com | 923160.com | 3242x.com | jing555.com | 4023i.com | 3016ccc.com | www.76060p.com | www.29886m.com | www.xpj395.com | www.cp55569.com | www.00772e.com | www.2566y3.com | www.0076788.com | www.32123p.com | www.927260.com | www.221836.com | 69990.com | 69111r.com | 22ff940.com | 4541n.com | 2613s.com | www.252388.com | www.23427q.com | www.62kjw.com | www.078999.com | www.55070s.com | www.hg860033.com | www.34788f.com | www.798288.com | 5651u.com | 0652c.com | vip4357.com | 2543003.com | www.7669d.net | www.79138.com | www.19yh9.com | www.452955.com | www.3890s.com | www.297126.com | 55797l.com | 0500o.com | 99151x.com | www.87680p.com | www.8722msc.com | www.88325r.com | www.53911c.com | www.591799.com | 6616xsj.com | bwinlll.com | h8381.com | www.56520d.com | www.g44c.com | www.780780d.com | www.444hy.cc | v61653.com | tzvip2022.com | 8036t.com | www.wns8833.com | www.4136u.com | www.83033y.com | www.391411.com | mf704.com | 506374.com | www.8694n.com | www.746824.com | www.725609.com | www.550424.com | 6572x.com | 2247000.com | www.88jt555.com | www.xpj718.com | www.05883.cc | 701679.com | 3559ooo.com | www.hg338338.com | www.20199ww.com | www.ky1006.com | www.50732e.com |